Neurotrophic activity of standardized extract of Centella asiatica ECa233 on human neuroblastoma cells

نویسندگان

  • Oraphan Wanakhachornkrai
  • Varisa Pongrakhananon
  • Preedakorn Chunhacha
  • Aree Wanasuntronwong
  • Anusara Vattanajun
  • Boonyong Tantisira
  • Pithi Chanvorachote
  • Mayuree H. Tantisira
چکیده

Inter-disciplinary Program in Physiology, Graduate School, Chulalongkorn University, Bangkok, Thailand. Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. Cell-based Drug and Health Product Development Research Unit., Chulalongkorn University, Bangkok, Thailand. Faculty of Dentistry, Mahidol University, Bangkok, Thailand Department of Physiology, Phramonkutklao College of Medicine, Bangkok, Thailand. Faculty of Pharmacy, Silpakorn University, Nakonprathom, Thailand. Faculty of Pharmaceutical Scienccs, Burapha University, Chonburi, Thailand.

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Neuritogenic effect of standardized extract of Centella asiatica ECa233 on human neuroblastoma cells

BACKGROUND In order to gain insight into neuroprotective effects of ECa 233, a standardized extract of Centella asiatica, previously demonstrated in animal models of memory impairment induced by transient global ischemia or intracerebroventricular injection of β-amyloid, the effect of ECa 233 on neurite outgrowth of human IMR-32 neuroblastoma cell line was investigated. METHODS Cells were see...

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تاریخ انتشار 2013